Signal transduction

Results: 1789



#Item
571Signal transduction / Genetics / A431 cells / Keratinocyte / Carcinogenesis / CHUK / Cell culture / Catenin / Cellular differentiation / Biology / Cell lines / Carcinogens

CYLD regulates keratinocyte differentiation and skin cancer progression in humans

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Source URL: www.nature.com

Language: English - Date: 2011-09-08 06:00:47
572Oncology / Antibiotics / Trichostatin A / Signal transduction / Histone deacetylase inhibitor / Histone deacetylase / NUMB / Phosphoinositide 3-kinase / Notch signaling pathway / Medicine / Chemistry / Biology

The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition of lens epithelial cells

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Source URL: www.nature.com

Language: English - Date: 2013-10-24 09:54:19
573Apoptosis / Immune system / Signal transduction / Protein families / Aryl hydrocarbon receptor / Fas receptor / Caspase / Tumor necrosis factor-alpha / Poly ADP ribose polymerase / Biology / Cell biology / Programmed cell death

Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis

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Source URL: www.nature.com

Language: English
574Gene delivery / Integrins / Laminin / Proteins / Transfection / Cell / B cell / Signal transduction / PEDF / Biology / Cell biology / Molecular biology

Extraribosomal functions associated with the C terminus of the 37/67 kDa laminin receptor are required for maintaining cell viability

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Source URL: www.nature.com

Language: English - Date: 2010-05-13 05:58:34
575Gynaecological cancer / Protein kinases / Genes / Wnt signaling pathway / Beta-catenin / Endometrial cancer / Endometrial hyperplasia / LRP5 / AKT / Biology / Medicine / Signal transduction

Inhibitory effect of 2-(piperidinoethoxyphenyl[removed]hydroxyphenyl)-2H-benzo(b)pyran (K-1) on human primary endometrial hyperplasial cells mediated via combined suppression of Wnt/β-catenin signaling and

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Source URL: www.nature.com

Language: English
576Genes / Signal transduction / Oncogenes / Carcinogenesis / Tumor suppressor genes / Wnt signaling pathway / Beta-catenin / CDH1 / Adenomatous polyposis coli / Biology / Genetics / Medicine

Enhancer of zeste homolog 2 activates wnt signaling through downregulating CXXC finger protein 4

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Source URL: www.nature.com

Language: English - Date: 2013-08-15 09:55:02
577Genes / Wnt signaling pathway / Beta-catenin / CDH1 / Catenin / Cadherin / Adherens junction / LRP5 / Myc / Biology / Signal transduction / Oncogenes

OPEN Citation: Cell Death and Disease[removed], e1346; doi:[removed]cddis[removed] & 2014 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis

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Source URL: www.nature.com

Language: English
578Apoptosis / Immune system / Cell signaling / Signal transduction / Apoptosome / Inhibitor of apoptosis / Caspase 3 / XIAP / Fas receptor / Biology / Cell biology / Programmed cell death

The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells

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Source URL: www.nature.com

Language: English - Date: 2014-02-27 10:02:30
579Gene expression / Transcription factors / Immune system / Proteins / STAT3 / Epidermal growth factor receptor / STAT protein / JAK-STAT signaling pathway / Mammalian target of rapamycin / Biology / Biochemistry / Signal transduction

Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening

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Source URL: www.nature.com

Language: English - Date: 2014-06-12 12:18:59
580Apoptosis / Proteins / Signal transduction / Autophagy / AKT / Bcl-2-associated X protein / PI3K/AKT/mTOR pathway / Dynamic random-access memory / P53 / Biology / Cell biology / Programmed cell death

Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria

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Source URL: www.nature.com

Language: English - Date: 2014-02-20 10:01:47
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